


cinnabarinus (AbR) were significantly increased. The gamma aminobutyric acid (GABA) contents in a laboratory abamectin resistant strain of T. Recently, an interesting phenomenon was identified in the carmine spider mite, Tetranychus cinnabarinus, an important pest in agriculture. Xu, Qiang He, LinĪbamectin has been widely used as an insecticide/acaricide for more than 30 years because of its superior bioactivity. Xu, Zhifeng Liu, Yanchao Wei, Peng Feng, Kaiyang Niu, Jinzhi Shen, Guangmao Lu, Wencai Xiao, Wei Wang, Jinjun Smagghe, Guy J. High Gama-Aminobutyric Acid Contents Involved in Abamectin Resistance and Predation, an Interesting Phenomenon in Spider Mites hominis and some species of cattle gastrointestinal helminths when compared with formulations of 0.5 per cent ivermectin and 0.5 per cent abamectin administered through the same route. The pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained high efficacy against R.

As to Cooperia punctata, there was no difference regarding efficacy results obtained by the avermectins combination and abamectin. Against Haemonchus placei and Oesophagostomum radiatum, the pour-on of ivermectin+ abamectin showed better efficacy than the 0.5 per cent ivermectin and 0.5 per cent abamectin.
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Cattle medicated with 1.5 per cent ivermectin +0.5 per cent abamectin, pour-on, remained free from parasitism by Dermatobia hominis larvae during 42 days (96 per cent efficacy), while values superior to 90 per cent were obtained by 0.5 per cent ivermectin (92 per cent) and 0.5 per cent abamectin (93 per cent) until the 42nd and 35th days post treatment, respectively. Against Cochliomyia hominivorax larvae, all pour-on formulations tested (1.5 per cent ivermectin +0.5 per cent abamectin, 0.5 per cent ivermectin and 0.5 per cent abamectin), as well as 1 per cent doramectin administered subcutaneously, were considered ineffective. The results of efficacy of the ivermectin+ abamectin and the 0.5 per cent ivermectin against Haematobia irritans were similar. Results obtained on trials against Rhipicephalus (Boophilus) microplus showed that the pour-on combination of 1.5 per cent ivermectin +0.5 per cent abamectin obtained superior efficacy indexes against this ectoparasite, when compared with formulations containing 0.5 per cent ivermectin, 1 per cent ivermectin and the combination of 1 per cent abamectin +20 per cent levamisole. The present work aimed to evaluate, through ten different studies, the therapeutic efficacy of a new pour-on formulation, containing 1.5 per cent ivermectin +0.5 per cent abamectin, against parasites of cattle. Silva, Heloisa Cristina Prette, Nancy Lopes, Welber Daniel Zanetti Sakamoto, Cláudio Alessandro M Buzzulini, Carolina Dos Santos, Thais Rabelo Cruz, Breno Cayeiro Teixeira, Weslen F Pires Felippelli, Gustavo Carvalho, Rafael Silveira Maciel, Willian Giquelin Soares, Vando Edésio da Costa, Alvimar José Endectocide activity of a pour-on formulation containing 1.5 per cent ivermectin +0.5 per cent abamectin in cattle.
